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Cochrane Skin Group

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Full list:

Emollients for eczema (protocol stage)
H1 antihistamines for eczema (protocol stage)
Interventions for melasma (protocol stage)
Interventions for morphea (protocol stage)
Light therapies for acne (protocol stage)
Methotrexate for psoriasis (protocol stage)
Oral isotretinoin for acne (protocol stage)
Oral retinoids for psoriasis (protocol stage)

By subtopic:

Skin Group (241)
A. INFECTIOUS DISEASES AFFECTING THE SKIN (35)
A0 Skin diseases caused by viruses: e.g.viral warts, herpes simplex (cold sores), herpes zoster (shingles), molluscum contagiosum; and diseases of suspected viral origin eg piytriasis rosea (21)
1. Preventive measures (0)
- reduction of transmission (0)
2. Medical treatments (15)
topical treatments (8)
- topical irritants (1)
Interventions for cutaneous molluscum contagiosum
- topical keratolytic agents (e.g. wart paints) (2)
Interventions for cutaneous molluscum contagiosum
Topical treatments for cutaneous warts
- retinoids (0)
- intralesional bleomycin (1)
Topical treatments for cutaneous warts
- antihistamines (1)
Interventions for pityriasis rosea
- corticosteroids (1)
Interventions for pityriasis rosea
- emollients (1)
Interventions for pityriasis rosea
- antiseptics (1)
Interventions for cutaneous molluscum contagiosum
systemic treatments (6)
- immunotherapy (1)
Topical treatments for cutaneous warts
- high dose cimetidine (1)
Interventions for cutaneous molluscum contagiosum
- retinoids (0)
- antiviral drugs (e.g. acyclovir) (1)
Interventions for pityriasis rosea
- corticosteroids (1)
Interventions for pityriasis rosea
- tricyclic antidepressants (0)
-antihistamines (1)
Interventions for pityriasis rosea
-antibacterials (1)
Interventions for pityriasis rosea
phototherapies (1)
Interventions for pityriasis rosea
3. Surgical procedures (5)
- cryotherapy (freezing) (2)
Interventions for cutaneous molluscum contagiosum
Topical treatments for cutaneous warts
- cautery (1)
Topical treatments for cutaneous warts
- surgical excision (1)
Topical treatments for cutaneous warts
- laser therapy (1)
Topical treatments for cutaneous warts
- phenol (0)
4. Alternative/complementary treatments eg hypnosis for warts (1)
- Homeopathic (1)
Interventions for cutaneous molluscum contagiosum
A20 Skin diseases caused by bacteria: e.g. impetigo, boils, folliculitis, cellulitis (Liaison with Cochrane Wounds Group for bacterial wound infections) (4)
1. Preventive (0)
- vaccination (0)
- reduction of transmission (0)
2. Medical treatments (4)
- topical antiseptics (1)
Interventions for impetigo
- topical antibiotics (1)
Interventions for impetigo
- systemic antibiotics (2)
Interventions for cellulitis and erysipelas (protocol stage)
Interventions for impetigo
- alternative/complementary treatments (0)
3. Surgical procedures (0)
- incision and drainage (0)
A30-31 Leprosy and its complications (2)
Interventions for erythema nodosum leprosum
Interventions for skin changes caused by nerve damage in leprosy
A32-35 Tuberculosis and related infections of the skin: e.g.lupus vulgaris, atypical mycobacterial infection (fish tank granuloma etc) (0)
1. Preventive (0)
- reduction of transmission (0)
2. Medical treatments (0)
- antibiotic therapy (0)
3. Surgical (0)
- Excision (0)
A5 Skin diseases caused by fungi, e.g. candidosis (thrush), dermatophytosis (ringworm) (5)
1. Preventive (0)
- reduction of transmission : e.g. for tinea pedis (athlete's foot), tinea capitis (scalp ringworm) (0)
2. Medical treatments (5)
- topical antifungal agents (1)
Topical treatments for fungal infections of the skin and nails of the foot.
- topical corticosteroid/antifungal preparations (0)
- oral antifungal agents (4)
Oral potassium iodide for the treatment of sporotrichosis
Oral treatments for fungal infections of the skin of the foot.
Oral treatments for toenail onychomycosis (protocol stage)
Systemic antifungal therapy for tinea capitis in children
- alternative/complementary treatments (0)
3. Surgical treatments (0)
3. Surgical treatments (0)
A6 Skin diseases caused by parasites e.g. scabies, head lice, onchocerciasis (3)
Interventions for American cutaneous and mucocutaneous leishmaniasis
Interventions for Old World cutaneous leishmaniasis
Vaccines for preventing cutaneous leishmaniasis (protocol stage)
B. SKIN CONDITIONS DUE TO ENVIRONMENTAL OR PHYSICAL INJURY (11)
B1 Pressure sores (0)
Please refer to Cochrane Wounds Group (0)
B2 Tattoos (0)
1. Preventive measures (0)
2. Removal (0)
- surgical (0)
- laser (0)
B5 Skin conditions caused or provoked by sunlight and ultraviolet radiation e.g. actinic (solar) keratoses, polymorphic light eruption, sun-induced skin ageing, photosensitivity dermatitis. Skin cancer is considered separately in sections X1 to X4. (11)
1. Preventive measures (2)
- public education campaigns (0)
sunscreens (2)
Interventions for photodamaged skin
Interventions for polymorphic light eruption (protocol stage)
2. Medical treatments (8)
- topical and oral corticosteroids (1)
Interventions for polymorphic light eruption (protocol stage)
- betacarotene for porphyrias (0)
- 5-fluoruracil for actinic keratoses (0)
- topical and systemic retinoids (1)
Interventions for photodamaged skin
- phototherapy, photochemotherapy (PUVA) (1)
Interventions for polymorphic light eruption (protocol stage)
- immunosuppressants (1)
Interventions for polymorphic light eruption (protocol stage)
- immunomodulators and anti-inflammatory agents (1)
Interventions for polymorphic light eruption (protocol stage)
- azathioprine or cyclosporin for photosensitivity dermatitis (0)
- antioxidants (1)
Interventions for photodamaged skin
- hydroxy acids (1)
Interventions for photodamaged skin
- combinations of the above (0)
- natural polysaccharides (1)
Interventions for photodamaged skin
3. Surgical procedures (1)
Interventions for photodamaged skin
C. DERMATITIS AND ECZEMA (28)
C1 Atopic dermatitis (atopic eczema, childhood eczema) (14)
1. Preventive measures (3)
- dietary (liaison with Cochrane Airways Group) (1)
Dietary exclusions for established atopic eczema
- reduction in airborne allergen exposure e.g. house dust mite (liaison with Cochrane Airways Group and Pregnancy and Childbirth Group) (0)
- use of emollients (moisturisers) (0)
- prevention of subsequent asthma in children with atopic dermatitis cetirizine (liaison with Cochrane Airways Group) (1)
Psychological and educational interventions for atopic eczema in children
- probiotics (1)
Probiotics for treating eczema
2. Medical Treatments (11)
Topical treatments (creams/ointments applied directly to the skin) (3)
- emollients (1)
Emollients for eczema (protocol stage)
- topical corticosteroids (0)
- tar preparations (0)
- impregnated bandages (tar, ichthammol etc) and "wet wraps" (0)
- corticosteroid/antibiotic combinations (0)
- calcineurin inhibitors (2)
Topical pimecrolimus for eczema
Topical tacrolimus for atopic dermatitis (protocol stage)
Systemic treatments (3)
- phototherapy, photochemotherapy (0)
- azathioprine (0)
- cyclosporin (0)
- antihistamines (1)
H1 antihistamines for eczema (protocol stage)
- evening primrose oil and borage oil (1)
Oral evening primrose oil and borage oil for atopic eczema (protocol stage)
- traditional chinese herbs (1)
Chinese herbal medicine for atopic eczema
Other approaches (5)
- reduction in environmental allergens (0)
- topical and systemic antimicrobial therapy (0)
- dietary approaches (2)
Dietary exclusions for established atopic eczema
Dietary supplements for established atopic eczema (protocol stage)
- psychological and educational approaches (e.g. habit reversal, hypnosis) (1)
Psychological and educational interventions for atopic eczema in children
- desensitisation (0)
- reduction of S aureus (1)
Interventions to reduce Staphylococcus aureus in the management of atopic eczema
- combinations of the above (1)
Interventions for hand eczema (protocol stage)
C2-C5 "Constitutional" Dermatitis e.g. seborrhoeic dermatitis (including dandruff, otitis externa), discoid eczema, pompholyx (8)
1. Prevention (0)
- use of soap substitutes (0)
2. Medical treatments (8)
- topical corticosteroids and combinations with other agents (1)
Interventions for seborrhoeic dermatitis (protocol stage)
- potassium permanganate and other astringents (0)
- antifungal agents (1)
Interventions for seborrhoeic dermatitis (protocol stage)
- topical lithium (1)
Interventions for seborrhoeic dermatitis (protocol stage)
- keratolytic shampoos (0)
- antibiotic therapy (0)
- superficial radiotherapy (0)
- phototherapy and photochemotherapy (1)
Interventions for seborrhoeic dermatitis (protocol stage)
- combinations of the above (2)
Interventions for hand eczema (protocol stage)
Interventions for seborrhoeic dermatitis (protocol stage)
-calcineurin inhibitors (2)
- topical tacrolimus (1)
Interventions for seborrhoeic dermatitis (protocol stage)
-topical pimecrolimus (1)
Interventions for seborrhoeic dermatitis (protocol stage)
C6-C8 Contact Dermatitis (allergic or irritant) e.g. nickel dermatitis, occupational hand dermatitis, "nappy rash" or "diaper rash". (6)
1. Preventive measures (4)
- modification of work practices (1)
Interventions for preventing occupational irritant hand dermatitis (protocol stage)
- removal of allergens/irritants from home or work environment or from diet (nickel) (0)
- disposable nappies (1)
Disposable nappies for preventing napkin dermatitis in infants
- protective clothing (e.g. gloves) (1)
Interventions for preventing occupational irritant hand dermatitis (protocol stage)
- barrier creams (1)
Interventions for preventing occupational irritant hand dermatitis (protocol stage)
- occupational health screening for individuals at high risk of dermatitis (0)
- soap substitutes (0)
2. Medical treatments (2)
Topical treatments (1)
- emollients (0)
- topical corticosteroids (0)
- corticosteroid/antibiotic combinations (0)
- superficial radiotherapy (0)
- topical vitamin A or derivatives (1)
Topical Vitamin A, or its derivatives, for treating and preventing napkin dermatitis in infants
Systemic treatments (0)
- systemic corticosteroids (0)
- azathioprine (0)
- cyclosporin (0)
- phototherapy, photochemotherapy (0)
- traditional chinese herbs (0)
- combinations of the above (1)
Interventions for hand eczema (protocol stage)
C9-CE Other eczematous reactions e.g. venous eczema (liaison with Cochrane Wounds Group), asteatotic dermatitis (0)
1. Prevention (0)
- emollients (0)
2. Medical treatment (0)
- emollients (including bath additives) (0)
- impregnated bandages (0)
- topical corticosteroids (0)
D. PSORIASIS AND OTHER KERATINISING DISORDERS (27)
D1 Psoriasis (27)
1. Preventive measures (1)
- reduction or cessation of tobacco smoking and/or alcohol consumption (liaison with Cochrane Tobacco Addiction Group) (0)
- stress reduction programmes (0)
- antistreptococcal interventions (tonsillectomy, antibiotics) (1)
Antistreptococcal interventions for guttate and chronic plaque psoriasis
2. Medical treatments (26)
Topical treatments (12)
- emollients (0)
- occlusion (0)
- salicylic acid (1)
Topical treatments for chronic plaque psoriasis
- tar preparations (1)
Topical treatments for chronic plaque psoriasis
- anthralin (dithranol) (1)
Topical treatments for chronic plaque psoriasis
- topical corticosteroids (3)
Interventions for chronic palmoplantar pustulosis
Interventions for nail psoriasis (protocol stage)
Topical treatments for chronic plaque psoriasis
- vitamin D analogues (1)
Topical treatments for chronic plaque psoriasis
- tacrolimus (1)
Topical treatments for chronic plaque psoriasis
- topical retinoids (1)
Topical treatments for chronic plaque psoriasis
- combinations of the above (3)
Interventions for chronic palmoplantar pustulosis
Interventions for guttate psoriasis
Topical treatments for chronic plaque psoriasis
Systemic treatments (13)
- biologics (1)
Biologics for chronic plaque psoriasis (protocol stage)
- phototherapy (1)
Interventions for nail psoriasis (protocol stage)
- photochemotherapy (1)
Interventions for chronic palmoplantar pustulosis
- methotrexate (1)
Methotrexate for psoriasis (protocol stage)
- cyclosporin (1)
Interventions for chronic palmoplantar pustulosis
- hydroxyurea (0)
- systemic retinoids (3)
Interventions for chronic palmoplantar pustulosis
Interventions for nail psoriasis (protocol stage)
Oral retinoids for psoriasis (protocol stage)
- oral Vitamin D analogues (0)
- fumarates (1)
Fumaric acid esters for psoriasis (protocol stage)
- combinations of the above (3)
Antistreptococcal interventions for guttate and chronic plaque psoriasis
Interventions for chronic palmoplantar pustulosis
Interventions for guttate psoriasis
- antibiotics (1)
Interventions for chronic palmoplantar pustulosis
Alternative/complementary treatments (1)
- psychological approaches (0)
- dietary fish supplements (0)
- Chinese herbs (1)
Traditional Chinese herbs for psoriasis (protocol stage)
- balneotherapy including spa waters and Dead Sea therapy (0)
- laser therapy (0)
- combinations of the above (0)
E. PAPULOSQUAMOUS DISORDERS INCLUDING LICHEN PLANUS; (6)
E0 Lichen planus (6)
- topical corticosteroids (2)
Interventions for cutaneous lichen planus (protocol stage)
Interventions for erosive lichen planus affecting mucosal sites (protocol stage)
- systemic corticosteroids (2)
Interventions for cutaneous lichen planus (protocol stage)
Interventions for erosive lichen planus affecting mucosal sites (protocol stage)
- cyclosporin (1)
Interventions for erosive lichen planus affecting mucosal sites (protocol stage)
- photochemotherapy (1)
Interventions for erosive lichen planus affecting mucosal sites (protocol stage)
E6 Granuloma annulare (0)
- intralesional corticosteroids (0)
- cutaneous injury including cryotherapy (0)
- nicotinamide (0)
E8 Cutaneous sarcoidosis (0)
- topical and intralesional corticosteroids (0)
- antimalarial therapy (0)
- methotrexate (liaison with Cochrane Airways Group) (0)
G. DISORDERS OF SKIN COLOUR (14)
G1 Increased skin pigmentation e.g. melasma (chloasma, mask of pregnancy) (4)
- topical sunscreens (liaison with Cochrane Pregnancy and Childbirth Group for preventing melasma in pregnancy) (1)
Interventions for melasma (protocol stage)
- azelaic acid (1)
Interventions for melasma (protocol stage)
- topical hydroquinone (1)
Interventions for melasma (protocol stage)
- topical retinoids (1)
Interventions for melasma (protocol stage)
G6 Decreased skin pigmentation e.g. vitiligo (leucoderma (9)
1. Medical treatments (8)
- phototherapy (psoralen + sunlight, photochemotherapy) (1)
Interventions for vitiligo
- topical treatments (6)
- topical steroids (1)
Interventions for vitiligo
- intralesional steroids (1)
Interventions for vitiligo
- topical calcipotriol (1)
Interventions for vitiligo
- tacrolimus (1)
Interventions for vitiligo
- khellin (1)
Interventions for vitiligo
- pseudocatalase (1)
Interventions for vitiligo
- systemic treatments (1)
Interventions for vitiligo
2. Surgical treatments (1)
- skin transplants (1)
Interventions for vitiligo
3. Complementary therapies (1)
Interventions for vitiligo
F. URTICARIA AND OTHER INFLAMMATORY SKIN DISORDERS (3)
F1-F9 Urticaria (hives) and angio-oedema (1)
- dietary measures (0)
- oral H1 antihistamines (1)
H1-antihistamines for chronic urticaria (protocol stage)
- oral H2 antihistamines (0)
- systemic corticosteroids (0)
- cyclosporin (0)
- anabolic steroids (for hereditary angio-oedema) (0)
FA2-3 Erythema multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis (2)
- systemic corticosteroids (1)
Interventions for toxic epidermal necrolysis
- prophylactic antiviral therapy (herpes simplex-induced erythema multiforme) (0)
- intensive care (toxic epidermal necrolysis) (1)
Interventions for toxic epidermal necrolysis
H. DISORDERS OF SKIN APPENDAGES (HAIR, NAILS, SWEAT GLANDS) (26)
H0 Nail disorders (1)
- medical treatments such as intralesional corticosteroids (1)
- surgical repair (1)
Interventions for ingrowing toenails
H10 Excessive hair growth (hirsutism) (1)
1. Non-medical treatments (1)
- electrolysis (0)
- bleaching (0)
- laser hair removal (1)
Laser and photoepilation for unwanted hair growth
2. Medical treatments (0)
- hormonal therapy ie anti-androgens such as spironolactone, cyproterone acetate (liaison with Cochrane Menstrual Disorders Group) (0)
H12 Hair loss e.g. alopecia areata ("alopecia"), androgenic alopecia (male-pattern balding) (7)
1. Medical treatments (7)
- systemic corticosteroids (1)
Interventions for alopecia areata
- topical immunotherapy (e.g. diphencyprone) (1)
Interventions for alopecia areata
- hormonal therapy (anti-androgens) (2)
Interventions for androgenic alopecia in women (protocol stage)
Non-surgical interventions for androgenetic alopecia in men (protocol stage)
- minoxidil (3)
Interventions for alopecia areata
Interventions for androgenic alopecia in women (protocol stage)
Non-surgical interventions for androgenetic alopecia in men (protocol stage)
2. Surgical treatments (0)
- hair transplant (0)
- scalp reduction (0)
H3 Acne (7)
Topical treatments (1)
- benzoyl peroxide (0)
- topical retinoids (1)
Topical retinoids for acne vulgaris (protocol stage)
- topical antibiotics (0)
- azelaic acid (0)
- adapalene (0)
- combinations of the above (0)
Oral treatments (2)
- oral antibiotics (1)
Minocycline for acne vulgaris: efficacy and safety
- oral isotretinoin (1)
Oral isotretinoin for acne (protocol stage)
- hormonal therapy such as anti-androgen therapy (liaison with Cochrane Menstrual Disorders Group) (0)
Alternative/complementary treatments (2)
Complementary therapies for acne vulgaris (protocol stage)
Light therapies for acne (protocol stage)
Behavioural treatments (1)
Tobacco smoking cessation for treating acne (protocol stage)
Treatment of acne scars (1)
- topical retinoids (0)
- surgical treatments (including dermabrasion) (0)
- laser therapy (1)
Laser resurfacing for facial acne scars
H4 Rosacea (4)
- topical metronidazole (1)
Interventions for rosacea
- oral antibiotics (1)
Interventions for rosacea
- oral isotretinoin (1)
Interventions for rosacea
- eradication of Demodex mites (1)
Interventions for rosacea
H6 Hidradenitis suppurativa and other disorders of the apocrine sweat glands (0)
1. Medical treatments (0)
- oral antibiotics (0)
- oral isotretinoin (0)
- anti-androgen therapy (liaison with Cochrane Menstrual Disorders Group) (0)
2. Surgical treatments (0)
- cryosurgery (0)
- excision of apocrine gland-bearing skin (0)
H7 Sweating disorders (6)
1. Medical treatments (4)
- topical aluminium salts and antiperspirants (1)
Interventions for localised excessive sweating (protocol stage)
- systemic beta-blockade (propranolol) (1)
Interventions for localised excessive sweating (protocol stage)
- oral anticholinergic therapy (1)
Interventions for localised excessive sweating (protocol stage)
- iontophoresis (1)
Interventions for localised excessive sweating (protocol stage)
2. Surgical treatments (2)
- excision of sweat glands (including axillary vault excision) (1)
Interventions for localised excessive sweating (protocol stage)
- sympathectomy (1)
Interventions for localised excessive sweating (protocol stage)
J. DISORDERS INVOLVING THE SKIN'S BLOOD & LYMPHATIC VESSELS (0)
J1 Ectasias of blood vessels in the skin (dilated blood vessels) (0)
- laser therapy (0)
- injection of sclerosing agents (0)
J3 Cutaneous vasculitis (inflammation of blood vessels in the skin) (0)
- systemic corticosteroids (0)
- dapsone (0)
- colchicine (0)
- immunosuppressive and cytotoxic drugs (cyclosporin, cyclophosphamide) (liaison with Cochrane Musculoskeletal Diseases Group) (0)
J9 Oedema and lymphoedema (liaison with Cochrane Peripheral Vascular Diseases Group) (0)
JB Blushing and flushing reactions (0)
Medical treatments (0)
- propranolol (0)
- antihistamines (0)
JD Raynaud's disease ("white finger") and related disorders (liaison with Cochrane Peripheral Vascular Diseases Group and Cochrane Musculoskeletal Group) (0)
K. DISORDERS OF THE DERMIS AND SUBCUTANEOUS TISSUE (0)
K01 Cutaneous striae (stretch marks) (liaison with Cochrane Pregnancy and Childbirth Group) (0)
K80 Panniculitis (inflammation of subcutaneous fat) (0)
- oral corticosteroids (0)
- antituberculous therapy (0)
M. CONNECTIVE TISSUE AND IMMUNOBULLOUS AND RELATED; (26)
M0 Lupus erythematosus (liaison with Cochrane Musculoskeletal Diseases Group) (0)
M0 Lupus erythematosus (7)
- photoprotection (1)
Drugs for discoid lupus erythematosus
- topical and intralesional (injected) corticosteroids (2)
Drugs for discoid lupus erythematosus
Interventions for cutaneous disease in systemic lupus erythematosus (protocol stage)
- antimalarial therapy (1)
Drugs for discoid lupus erythematosus
- thalidomide (1)
Drugs for discoid lupus erythematosus
- systemic corticosteroids (2)
Drugs for discoid lupus erythematosus
Interventions for cutaneous disease in systemic lupus erythematosus (protocol stage)
M1 Systemic sclerosis (systemic scleroderma) (liaison with Cochrane Musculoskeletal Diseases Group) (0)
- systemic corticosteroids (0)
- penicillamine (0)
- extracorporeal photochemotherapy (0)
M2 Morphoea and related conditions (4)
- topical treatments (1)
Interventions for morphea (protocol stage)
- systemic treatments (1)
Interventions for morphea (protocol stage)
- intralesional treatments (1)
Interventions for morphea (protocol stage)
- intravenous treatments (1)
Interventions for morphea (protocol stage)
M4 Lichen sclerosus & related conditions (4)
cryotherapy (1)
Topical interventions for genital lichen sclerosus (protocol stage)
light therapies (1)
Topical interventions for genital lichen sclerosus (protocol stage)
topical treatments (1)
Topical interventions for genital lichen sclerosus (protocol stage)
ultrasound (1)
Topical interventions for genital lichen sclerosus (protocol stage)
M5 Dermatomyositis (liaison with Cochrane Musculoskeletal Diseases Group) (0)
- systemic immunosuppressive agents (0)
ME Immunobullous (blistering) disorders of the skin e.g bullous pemphigoid, pemphigus, dermatitis herpetiformis) (11)
- topical corticosteroids (1)
Interventions for pemphigus vulgaris and pemphigus foliaceus
- systemic corticosteroids (0)
- immunosuppressive therapy (e.g. azathioprine, cyclosporin, cyclophosphamide) (2)
Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita
Interventions for pemphigus vulgaris and pemphigus foliaceus
- dapsone (2)
Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita
Interventions for pemphigus vulgaris and pemphigus foliaceus
- long-acting sulphonamides (0)
- minocycline (1)
Interventions for pemphigus vulgaris and pemphigus foliaceus
- plasma exchange (1)
Interventions for pemphigus vulgaris and pemphigus foliaceus
- gluten-free diet (0)
- combinations of the above (0)
- drug treatments (any) (3)
Interventions for bullous pemphigoid
Interventions for mucous membrane pemphigoid and epidermolysis bullosa acquisita
Interventions for pemphigus vulgaris and pemphigus foliaceus
intralesional corticosteroid (1)
Interventions for pemphigus vulgaris and pemphigus foliaceus
N. METABOLIC AND NUTRITIONAL DISORDERS AFFECTING THE SKIN (0)
N4 Porphyrias affecting the skin (0)
- venesection (0)
- antimalarials (0)
P. PSYCHOLOGICAL, PSYCHIATRIC AND RELATED DISORDERS OF THE SKIN (0)
P0 Pruritus and skin itching e.g. "senile pruritus", pregnancy itch, uraemic pruritus (0)
- emollients (0)
- aspirin (liaison with Cochrane Pregnancy and Childbirth Group for itching in pregnancy) (0)
- phototherapy (0)
- opiate antagonists (0)
- use of non-biological washing powder (0)
- alternative/complementary treatments (0)
- combinations of the above (0)
P1 Self-inflicted skin disease including dermatitis artefacta (0)
- psychotherapy (0)
- behaviour therapy (0)
- antipsychotic agents (0)
P3 Disorders of cutaneous image and perception including delusional psychosis affecting the skin (0)
- pimozide (0)
- psychiatric therapy (0)
R. SKIN DISEASE RESULTING FROM DRUGS OR TREATMENT --see FA2-FA3 (0)
S. GENETIC AND CHROMOSOMAL DISORDERS AFFECTING THE SKIN (1)
S4 Ichthyoses (inherited scaling disorders of the skin) (1)
- emollients (0)
- urea (0)
- systemic retinoids (1)
Systemic retinoids for ichthyosis in children (protocol stage)
SA Epidermolysis bullosa (inherited blistering disorders of the skin) (0)
1. Medical treatments (0)
- phenytoin (0)
2. Surgical treatments (0)
- correction of deformity (0)
W. BIRTH MARKS AND DEVELOPMENTAL ABNORMALITIES OF THE SKIN (15)
Vascular birthmarks e.g infantile haemangiomas (6)
corticosteroids (1)
Interventions for infantile haemangiomas (protocol stage)
lasers (1)
Interventions for infantile haemangiomas (protocol stage)
- bleomycin (1)
Interventions for infantile haemangiomas (protocol stage)
- imiquimod (1)
Interventions for infantile haemangiomas (protocol stage)
interferon (1)
Interventions for infantile haemangiomas (protocol stage)
surgery (1)
Interventions for infantile haemangiomas (protocol stage)
W6 Vascular malformations e.g. port-wine stains (9)
- bleomycin (1)
Interventions for infantile haemangiomas (protocol stage)
- imiquimod (1)
Interventions for infantile haemangiomas (protocol stage)
- interferon (1)
Interventions for infantile haemangiomas (protocol stage)
- intralesional steroids (1)
Interventions for infantile haemangiomas (protocol stage)
- laser therapy (2)
Interventions for infantile haemangiomas (protocol stage)
Lasers and light sources for port-wine stains (protocol stage)
- other forms of light therapy (0)
- systemic steroids (1)
Interventions for infantile haemangiomas (protocol stage)
- topical steroids (1)
Interventions for infantile haemangiomas (protocol stage)
- vincristine (1)
Interventions for infantile haemangiomas (protocol stage)
X. TUMOURS AND CYSTS OF THE SKIN AND APPENDAGES (49)
X0, X3 Benign tumours of the skin e.g. seborrhoeic warts, benign "moles" (see also B5) (0)
- cryotherapy (0)
- surgical removal (0)
- laser therapy (0)
X1-X2 Non-melanoma cancer and precancer of the skin e.g. Bowen's disease, squamous cell carcinoma, basal cell carcinoma ("rodent ulcer") (42)
1. Preventive (7)
- primary and secondary prevention by education (1)
Educational programmes for skin cancer prevention (protocol stage)
- prevention in high risk groups (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
- reduction of suspected harmful exposures to ultraviolet radiation (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
- topical and systemic retinoids (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
- antioxidants (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
- dietary modifications (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
- complementary therapies (1)
Interventions for preventing non-melanoma skin cancers in high-risk groups
2. Medical treatment (10)
- topical 5-fluorouracil (3)
Interventions for Bowen's Disease (protocol stage)
Interventions for actinic keratoses (protocol stage)
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- other topicals (4)
Interventions for Bowen's Disease (protocol stage)
Interventions for actinic keratoses (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- interferon (2)
Interventions for actinic keratoses (protocol stage)
Interventions for basal cell carcinoma of the skin
- systemic treatments (1)
Interventions for basal cell carcinoma of the skin
3. Surgical treatment (17)
- curettage and electrocautery (4)
Interventions for Bowen's Disease (protocol stage)
Interventions for actinic keratoses (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- surgical excision (3)
Interventions for Bowen's Disease (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- cryosurgery (4)
Interventions for Bowen's Disease (protocol stage)
Interventions for actinic keratoses (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- micrographic (Mohs') surgery (3)
Interventions for Bowen's Disease (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
- laser surgery (3)
Interventions for Bowen's Disease (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
4. Other treatments (8)
- photodynamic therapy (5)
Interventions for Bowen's Disease (protocol stage)
Interventions for actinic keratoses (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
Photodynamic therapy for localised squamous cell carcinoma of the skin and its precursors (protocol stage)
- radiotherapy (3)
Interventions for Bowen's Disease (protocol stage)
Interventions for basal cell carcinoma of the skin
Interventions for non-metastatic squamous cell carcinoma of the skin (protocol stage)
X4 Malignant melanoma (7)
1.Preventive (3)
- primary and secondary prevention by education (1)
Educational programmes for skin cancer prevention (protocol stage)
- screening of high risk groups (0)
- reduction of suspected harmful exposures to ultraviolet radiation (0)
- preventative agents (2)
Cox-2 Inhibitors in the Prevention of Melanoma (protocol stage)
Statins and fibrates for preventing melanoma
2. Medical treatment (3)
- cytotoxic chemotherapy (2)
Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
Systemic treatments for metastatic cutaneous melanoma
- isolated limb perfusion (0)
- immunotherapy (interferon) (1)
Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
3. Surgical treatment (1)
- margins of surgical excision (1)
Surgical excision margins for primary cutaneous melanoma
- regional lymph node dissection (0)
- sentinel node biopsy (0)
Y BENIGN AND MALIGNANT INFILTRATIONS OF THE SKIN (0)
Y2 Cutaneous T-cell lymphoma (mycosis fungoides (0)
- photochemotherapy (0)
- topical mechlorethamine (nitrogen mustard) (0)
- topical corticosteroids (0)
- oral retinoids (0)
- interferon (0)
- electron beam therapy (0)
- radiotherapy (0)
- extracorporeal photochemotherapy (0)
- cytotoxic chemotherapy (0)

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